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If you are using Windows Server 2008 and you are getting an error when trying to Save your changes in Studio then you can set the application to be run as an Administrator.

Right click on the Astun.iShareMaps.Studio.Shell.exe in the Studio folder and select Properties.
Click on the Compatibility tab.

iShare Help > Running iShare Studio as an Administrator > image2015-2-5 16:21:35.png

Check the box “Run this program as an administrator”.
Click OK.